6533b820fe1ef96bd127a396

RESEARCH PRODUCT

ChemInform Abstract: Polycondensed Nitrogen Heterocycles. Part 24. Pyrrolo(3,4-c) isoquinolinone by Thermal Rearrangement of a Pyrrolylbenzotriazinone.

Francesco MingoiaEnrico AielloGaetano DattoloPatrizia DianaGirolamo CirrincioneAnna Maria Almerico

subject

chemistry.chemical_compoundchemistryThermalOrganic chemistrychemistry.chemical_elementGeneral MedicineIsoquinolineRing (chemistry)Medicinal chemistryNitrogenDerivative (chemistry)

description

Rearrangement under acidic conditions of the pyrrolylbenzotriazinone 7 afforded the pyrrolylbenzamides 10 and 11. By thermal rearrangement instead, the first fully aromatic derivative of the pyrrolo[3,4-c]isoquinoline ring system 9 was obtained.

https://doi.org/10.1002/chin.199306192