Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana

6533b821fe1ef96bd127ba6b

RESEARCH PRODUCT

Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana

Brice Cedric K. Atontsa Gabin Thierry M. Bitchagno James D. Simo Mpetga Brice Elvis N. Wamba Paul Nayim Roland T. Tchuenguem Blanche L. Ndontsa Romeol R. Koagne Till Opatz Victor Kuete Pierre Tane

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description

A new caffeate derivative from the ethanol extract of the stem bark of Cassia sieberiana DC. is described herein along with the known secondary metabolites spectaline (2), iso-6-cassine (3), 3-O-methyl-chiro-inositol (4), monobehenin (5), octyl nonadecyloate (6), β-sitosterol (7), stigmasterol (8) and sitosterol 3-O-β-D-glucopyranoside (9). The chemical structures were elucidated by means of various spectroscopic and spectrometric techniques. Extract and isolated compounds were devoid of inhibitory action against the herein selected bacterial strains (MICs > 256 μg/mL) but showed capacities to reduce 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (EC50 50 6.47 ± 0.48 μg/mL).

year	journal	country	edition	language
2019-01-01

https://dx.doi.org/10.6084/m9.figshare.10120826

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