6533b821fe1ef96bd127babd

RESEARCH PRODUCT

The Properdin System: Composition and Function

Volker Brade

subject

Chemical PhenomenaProperdinChemistryChemistry PhysicalGuinea PigsComplement C5Complement C3Complement C3-C5 ConvertasesHematologyGeneral MedicineCell biologyC5-convertaseRegulatory controlImmunologyComplement C3bProperdinAnimalsHumansComplement Factor DFunction (biology)Complement Factor B

description

. This article summarizes the physicochemical data on the factors which compose the properdin system in guinea pig and man. The following other topics are discussed: (1) Activation of the properdin system; (2) Formation of the initiating and amplification C3 convertases; (3) Formation of the C5 convertase, and (4) Regulatory control mechanisms of the properdin system.

https://doi.org/10.1159/000465190