6533b821fe1ef96bd127c13d

RESEARCH PRODUCT

ChemInform Abstract: Acid-Mediated Reaction of Bis(pyridine)iodonium(I) Tetrafluoroborate with Aromatic Compounds. A Selective and General Iodination Method.

José M. GonzálezJosé BarluengaPedro J. CamposMiguel A. García-martínGregorio AsensioGregorio AsensioGregorio Asensio

subject

chemistry.chemical_compoundTetrafluoroboratechemistryPyridineHalogenationRegioselectivityGeneral MedicineMedicinal chemistryChemical societyBis(pyridine)iodonium(I) tetrafluoroborate

description

Reaction of aromatic compounds with bis(pyridine)iodonium(I) tetrafluoroborate (IPy2BF4) in the presence of HBF4 or CF3SO3H in CH2Cl2 at room temperature furnishes monoiodo derivatives with excellent regioselectivity and yields. Use of either acid gives comparable results with activated aromatics, whereas CF3SO3H is much more effective in the iodination of deactivated aromatics. © 1993 American Chemical Society.

yearjournalcountryeditionlanguage
2010-08-20ChemInform
https://doi.org/10.1002/chin.199333101