6533b822fe1ef96bd127cbee
RESEARCH PRODUCT
The ten grand challenges of synthetic life
Vitor A. Dos SantosManuel PorcarAndrés MoyaAntoine DanchinVíctor De LorenzoSteen RasmussenSteen RasmussenNatalio Krasnogorsubject
Computer scienceSystems biology0206 medical engineeringBioengineering02 engineering and technologyBioinformaticsTask (project management)03 medical and health sciencesSynthetic biologyArtificial lifeMilestone (project management)Systems and Synthetic BiologyChallengesMolecular BiologySynthetic biologyVLAG030304 developmental biologyGrand ChallengesStreamlined genomesSysteem en Synthetische Biologie0303 health sciencesData scienceArtificial lifeCommentary020602 bioinformaticsBiotechnologydescription
The construction of artificial life is one of the main scientific challenges of the Synthetic Biology era. Advances in DNA synthesis and a better understanding of regulatory processes make the goal of constructing the first artificial cell a realistic possibility. This would be both a fundamental scientific milestone and a starting point of a vast range of applications, from biofuel production to drug design. However, several major issues might hamper the objective of achieving an artificial cell. From the bottom-up to the selection-based strategies, this work encompasses the ten grand challenges synthetic biologists will have to be aware of in order to cope with the task of creating life in the lab.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-06-01 |