6533b822fe1ef96bd127cc25

RESEARCH PRODUCT

The role of the substantia nigra in the control of amygdaloid paroxysmal activity.

Filippina SorberaGiuseppe AmatoGiuseppe CrescimannoV. La Grutta

subject

Kainic acidElectroshockCATSKainic AcidPhysiologyCaudate nucleusStimulationSubstantia nigraStriatumAmygdalaBiochemistryAmygdalaSubstantia Nigrachemistry.chemical_compoundmedicine.anatomical_structurenervous systemchemistrySeizuresTegmentummedicineCatsAnimalsCaudate NucleusNeuroscience

description

AbstractBoth in acute and chronic cats, focal paroxysmal activity evoked in the ventro-basal complex of the amygdala has been inhibited by substantia nigra conditioning stimulation, to a greater extent, than by caudate nucleus activation. Injection of kainic acid into substantia nigra resulted in the disappearance of the caudate inhibition. It is suggested that the final control, exerted by the striatum on the amygdaloid seizures, occurs by means of the substantia nigra.

10.3109/13813458109073987https://pubmed.ncbi.nlm.nih.gov/6167236