6533b822fe1ef96bd127ce15

RESEARCH PRODUCT

Independence of first- and second-order memories in newborn rabbits

Virginie JolyBernard HarsBenoist SchaalGérard CoureaudSolène Languille

subject

MaleAging[SDV]Life Sciences [q-bio]MESH: Mental RecallMESH: RabbitsMESH: Conditioning OperantPheromonesMESH : PheromonesMESH: Animals NewbornDevelopmental psychologyMESH : Learning0302 clinical medicineMESH: SmellComputingMilieux_COMPUTERSANDEDUCATIONMESH : FemaleMESH: AgingMESH: AnimalsMESH: MemoryMESH : AnisomycinProtein Synthesis InhibitorsMESH: Pheromones0303 health sciencesMESH : Animals NewbornMESH : MemoryMESH : OdorsSmellNeuropsychology and Physiological PsychologyMESH : MotivationFemaleMemory consolidationRabbitsmedicine.symptomMESH: AmnesiaPsychologyAnisomycinpsychological phenomena and processesOlfactory perceptionMESH : MaleCognitive NeuroscienceMESH: MotivationAmnesiaMESH: AnisomycinMESH : Conditioning Operant03 medical and health sciencesCellular and Molecular NeuroscienceMESH : AmnesiaMemoryparasitic diseasesmedicineAnimalsLearningMESH : RabbitsMESH : Protein Synthesis Inhibitors030304 developmental biologyMotivationMESH: Odors[ SDV ] Life Sciences [q-bio]MESH: Protein Synthesis InhibitorsRecallMESH : Mental RecallMESH : AgingMESH: MaleAnimals NewbornOdorMental RecallOdorantsConditioning OperantMESH : Smell MESH: LearningAmnesiaMESH : AnimalsMESH: FemaleNeuroscience030217 neurology & neurosurgery

description

WOS:000291649400006; International audience; The mammary pheromone promotes the acquisition of novel odorants (CS1) in newborn rabbits. Here, experiments pinpoint that CS1 becomes able to support neonatal learning of other odorants (CS2). We therefore evaluated whether these first- and second-order memories remained dependent after reactivation. Amnesia induced after CS2 recall selectively blocked this memory, when recall and amnesia of CS1 left the souvenir of CS2 safe; this finding partially differed from results obtained in adult mammals. Thus, in this model of neonatal appetitive odor learning, second-order memory seems to depend on first-order memory for its formation but not for its maintenance.

yearjournalcountryeditionlanguage
2011-06-01Learning & Memory
https://doi.org/10.1101/lm.2145111