6533b822fe1ef96bd127d7da
RESEARCH PRODUCT
Overcoming the PEG-addiction: well-defined alternatives to PEG from structure-property relationships to better defined therapeutics
Matthias BarzMaría J. VicentRudolf ZentelRobert Luxenhofersubject
Polymers and PlasticsComputer scienceOrganic ChemistryStructure propertyBioengineeringNanotechnology02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesBiochemistry0104 chemical scienceschemistry.chemical_compoundchemistryPEG ratio0210 nano-technologyEthylene glycoldescription
Synthetic methods in polymer chemistry have evolved tremendously during the last decade. Nowadays more and more attention is devoted to the application of those tools in the development of the next generation of nanomedicines. Nevertheless, poly(ethylene glycol) (PEG) remains the most frequently used polymer for biomedical applications. In this review, we try to summarize recent efforts and developments in controlled polymerisation techniques that may allow alternatives to PEG based systems and can be used to improve the properties of future polymer therapeutics.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 |