6533b822fe1ef96bd127ddbb
RESEARCH PRODUCT
Gingival neurofibroma in a neurofibromatosis type 1 patient: Case report
J.a. García De MarcosAlicia Dean FerrerFrancisco Alamillos GranadosJ.j. Ruiz MaseraM.j. García De MarcosA. Vidal JiménezB. Valenzuela SalasAna García Lainezsubject
gumUNESCO::CIENCIAS MÉDICASNF-I:CIENCIAS MÉDICAS [UNESCO]Von Recklinghausens diseaseType I neurofibromatosisneurofibromadescription
Neurofibroma is a benign peripheral nerve sheath tumour. It is one of the most frequent tumours of neural origin and its presence is one of the clinical criteria for the diagnosis of type 1 neurofibromatosis (NF-I). Neurofibromatosis type 1 is an autosomal dominantly inherited disease due to an alteration in the long arm of chromosome 17. About 50% of NF-I patients have no family history of the disease. NF-I patients have skin lesions (café au lait spots and neurofibromas) as well as bone malformations and central nervous system tumours. Diagnosis is based on a series of clinical criteria. Gingival neurofibroma in NF-I is uncommon. Treatment of neurofibromas is surgical resection. The aim of this paper is to report a case of NF-I with gingival involvement and to review the literature.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-01-01 |