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RESEARCH PRODUCT
0283: Correlation between N-terminal pro-natriuretic peptide levels and left atrial size in patients with left ventricular systolic dysfunction
Nizar Ben MansourK. TaamallahHouaida MahfoudhiWafa FehriHabib HaoualaI. HamdiFares Meznisubject
medicine.medical_specialtyEjection fractionmedicine.drug_classbusiness.industryDiastoleMean ageEndocrinologyLeft atrialInternal medicineNatriuretic peptidemedicineCardiologycardiovascular systemIn patientcardiovascular diseasesCardiology and Cardiovascular MedicinebusinessVentricular fillingdescription
BackgroundElevated N-terminal Pro B-type Natriuretic Peptide (NT Pro-BNP) levels are correlated with the severity of left ventricular systolic dysfunction and left ventricular filling alterations. Besides, left atrial (LA) size is believed to reflect chronic diastolic dysfunction.AimEvaluate the relationship between NT Pro-BNP and LA size.Methods81 patients (77.7% males; mean age, 61.55±15 years), with left ventricular systolic dysfunction (left ventricular ejection fraction [LVEF] 20cm2 was 1188pg/mL (area under the receiver-operating characteristic curve [AUC] 0.83 [0.71–0.93], p<0.0001, sensitivity 77.6%, specificity 75%).ConclusionThe present study shows that plasma NT Pro-BNP levels is strongly correlated to LA size. NT-proBNP level more than 1188pg/mL may suggest LA dilatation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-04-01 | Archives of Cardiovascular Diseases Supplements |