6533b823fe1ef96bd127e1b5
RESEARCH PRODUCT
Palladium-Catalyzed Dehydrogenative β’-Arylation of β-Keto Esters under Aerobic Conditions: Interplay of Metal and Brønsted Acids
Mikko V. LeskinenPetri M. PihkoRoshan Y. NimjeKai-tai Yipsubject
Organic ChemistryRegioselectivitychemistry.chemical_elementGeneral ChemistryCatalysisCatalysisMetalchemistry.chemical_compoundchemistryvisual_artvisual_art.visual_art_mediumOrganic chemistryPhenolsBrønsted–Lowry acid–base theoryta116Palladiumdescription
The Bronsted aids: The first dehydrogenative arylation of β-keto esters with arenes under ambient aerobic conditions is described. Under a Pd(II)/Bronsted acid co-catalytic system, regioselective arylations with alkoxylated arenes and phenols were achieved in good yields, even in gram-scale conditions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-08-22 | Chemistry : A European Journal |