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RESEARCH PRODUCT
Photochemical Derivatization and Fluorimetric Determination of Promethazine in a FIA Assembly
J. Martínez CalatayudA. Mellado RomeroC. Gómez Benitosubject
ChromatographyAqueous solutionCalibration curveBiochemistry (medical)Clinical BiochemistryBiochemistryDosage formFluorescence spectroscopyAnalytical ChemistryPromethazinechemistry.chemical_compoundchemistryElectrochemistrymedicineDerivatizationSpectroscopymedicine.drugdescription
Abstract The flow injection fluorimetric determination of promethazine is carried out by on-line photoderivatization. The PTFE tubing is helically coiled around the lamp. An analytical procedure is proposed by using aqueous solution as carrier stream: the calibration graph is linear over the range 0.05 - 20 ppm. The influence of foreign compounds is studied and the method is applied to promethazine determination in pharmaceutical formulations.
year | journal | country | edition | language |
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1992-07-01 | Analytical Letters |