6533b823fe1ef96bd127e99d

RESEARCH PRODUCT

Photochemical Derivatization and Fluorimetric Determination of Promethazine in a FIA Assembly

J. Martínez CalatayudA. Mellado RomeroC. Gómez Benito

subject

ChromatographyAqueous solutionCalibration curveBiochemistry (medical)Clinical BiochemistryBiochemistryDosage formFluorescence spectroscopyAnalytical ChemistryPromethazinechemistry.chemical_compoundchemistryElectrochemistrymedicineDerivatizationSpectroscopymedicine.drug

description

Abstract The flow injection fluorimetric determination of promethazine is carried out by on-line photoderivatization. The PTFE tubing is helically coiled around the lamp. An analytical procedure is proposed by using aqueous solution as carrier stream: the calibration graph is linear over the range 0.05 - 20 ppm. The influence of foreign compounds is studied and the method is applied to promethazine determination in pharmaceutical formulations.

https://doi.org/10.1080/00032719208016129