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RESEARCH PRODUCT
Calix[4]arenes with alkylidene bridges, synthesis and conformational properties
Iris ThondorfCordula GrüttnerVolker BöhmerSilvio E. BialiFlavio GrynszpanWalter Vogtsubject
Carbon atomChemistryStereochemistryOrganic ChemistryDrug DiscoveryCondensationBiochemistrydescription
Abstract Calix[4]arenes with one or two alkylidene bridges were synthesized by “2+2” fragment condensation. As predicted by molecular mechanics calculations aliphatic residues at the bridging carbon atom(s) prefer the equatorial position.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-08-01 | Tetrahedron Letters |