6533b823fe1ef96bd127f103
RESEARCH PRODUCT
Towards bioarrays of cellular-like compartments for monitoring few molecular binding events
Giuseppe Domenico ArrabitoFelicia CavaleriVincenza MontalbanoValeria VetriMaurizio LeoneBruno Giuseppe Pignatarosubject
Water-in-oil droplets inkjet printing Raster Image Correlation SpectroscopySettore CHIM/01 - Chimica Analiticadescription
The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |