6533b824fe1ef96bd1280148

RESEARCH PRODUCT

Inter-relationship between platelet-derived microparticles and oxidative stress in patients with venous thromboembolism

Domenico Di RaimondoPietro ZuccarelloMaria FioreIlenia NicolosiSalvatore Santo SignorelliLuca ZanoliGea Oliveri ContiAgostino GaudioMargherita FerranteAntonio CristaldiMaria Grazia Elfio

subject

medicine.medical_specialtyPhysiologyThiobarbituric acidvenous thromboembolismClinical Biochemistry030204 cardiovascular system & hematologymedicine.disease_causeBiochemistryGastroenterologyPathophysiologyArticleSuperoxide dismutase03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePlatelet degranulationInternal medicinemedicineTBARSoxidative stressPlateletcardiovascular diseases030212 general & internal medicineMolecular BiologymicroparticlesVenous thromboembolism.biologybusiness.industrylcsh:RM1-950PlateletbiomarkersCell BiologyBiomarkerequipment and suppliesMalondialdehydelcsh:Therapeutics. PharmacologyClotting timechemistryMicroparticleplateletsbiology.proteinOxidative strebusinessOxidative stress

description

Background: Hypercoagulative conditions play a key role in venous thromboembolism (VTE). Inflammation is currently linked to VTE, but the potential role of circulating microparticles and oxidative stress (OxS) must be elucidated. The aim of this study was to evaluate platelet-derived microparticles and surrogate OxS biomarkers in patients diagnosed with VTE through a case&ndash

10.3390/antiox9121217http://hdl.handle.net/10447/490920