6533b824fe1ef96bd1280b9b

RESEARCH PRODUCT

[2,5-Bis(dipropylamino)-4-(hydroxymethyl)phenyl]methanol

Gideon HolzmannHeiner DetertDieter SchollmeyerVolker Schmitt

subject

Diethyl succinatecrystal structurehydrogen bondCrystallographyChemistryHydrogen bondalcoholAlcoholCrystal structureDihedral angleRing (chemistry)Medicinal chemistryCrystalchemistry.chemical_compoundQD901-999phenylenediamineMethanol

description

The centrosymmetric title compound, C22H36N2O2, was prepared in five steps from diethyl succinate. The dipropylamino groups are almost orthogonal to the central phenylenedimethanol ring [dihedral angle = 87.62 (9)°]. In the crystal, the molecules are connected by O—H...N hydrogen bonds, forming (101) layers separated by the propyl chains.

10.1107/s2414314621004430http://scripts.iucr.org/cgi-bin/paper?S2414314621004430