Fluorescent chemosensors based on cyclohexane: selective sensing of succinate and malonate versus their longer or shorter homologues

6533b824fe1ef96bd12812bb

RESEARCH PRODUCT

Fluorescent chemosensors based on cyclohexane: selective sensing of succinate and malonate versus their longer or shorter homologues

Ana M. Costero Ursula Llaosa Pablo Gaviña Salvador Gil Manuel Colera

subject

chemistry.chemical_compound Malonate chemistry Cyclohexane Thiourea Organic Chemistry Drug Discovery Intermolecular force Photochemistry Biochemistry Medicinal chemistry Fluorescence Naphthalene

description

The sensing properties towards aliphatic α,ω-dicarboxylates of five cyclohexane-based ligands are described. The studied ligands have been designed following the binding site-signalling unit approach and they all possess thiourea groups as recognition moieties. Ligands 1 and 3 containing naphthalene units can be used as fluorescent sensors as they form intra- or intermolecular excimers in the presence of appropriate dicarboxylates. Selective sensing of succinate and malonate versus their longer or shorter homologues has been observed.

year	journal	country	edition	language
2008-07-01	Tetrahedron

https://doi.org/10.1016/j.tet.2008.05.064

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