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RESEARCH PRODUCT
Do zwitterionic species exist in the non-enzymatic peptide bond formation?
Juan BertránKatarzyna ŚWiderekIñaki TuñónSergio MartíVicent Molinersubject
IonsModels MolecularAqueous solutionChemistryMetals and AlloysGeneral ChemistryZwitterionicCombinatorial chemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsPeptide bondNon enzymaticMaterials ChemistryCeramics and CompositesQuantum TheoryThermodynamicsPeptide bondOrganic chemistryPeptidesdescription
The use of proper computational methods and models has allowed answering the controversial question of whether zwitterionic species exist in the mechanism of peptide bond synthesis in aqueous solution. In fact, the different conformations of zwitterionic species open the door to different mechanistic paths.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-01-01 | Chemical Communications |