6533b825fe1ef96bd1282055

RESEARCH PRODUCT

Intramuscular tranexamic acid

Anthony AbsalomBeverley J. HuntAndrea Cortegiani

subject

Clinical pharmacologybusiness.industryMORTALITYPOSTPARTUM HEMORRHAGEPostpartum haemorrhageAntifibrinolytic Agentstranexamic acidlaw.inventionAnesthesiology and Pain MedicinetraumaPharmacokineticsPregnancylawpostpartum haemorrhageAnesthesiaManagement of Technology and InnovationmedicineHumansFemaleclinical pharmacologybusinesspharmacokineticsTranexamic acidmedicine.drug

description

For many anaesthetists around the world, the mere mention of the word ‘pharmacokinetics’ is sufficient to make their eyes glaze over and their attention wander. Pharmacokinetics is seen as an art that is as obscure and esoteric as the art of divination (prediction) practiced by the likes of Professor Sybille Trelawny 1 but that has varying and mostly limited relevance to clinical practice. Although this hyperbole may have elements of truth, it is a fact that pharmacokinetic data are the essential foundation upon which rational drug dosing guidelines are developed for all drugs.

yearjournalcountryeditionlanguage
2021-01-01British Journal of Anaesthesia
10.1016/j.bja.2020.10.003https://doi.org/10.1016/j.bja.2020.10.003