6533b825fe1ef96bd12820c8
RESEARCH PRODUCT
NMR, X-Ray and MS Investigations of Ethyl 2-Aroyl-and Ethyl 2-Arylcarbamoyl-4,5- dimethyl-1,2,3,6-tetrahydropyridazine-1- carboxylates: Flexible Multidentate Ligands
Wolf-dieter RudorfKatri LaihiaPeter MeyerK. PihlajaMaija NissinenAlexander PerjéssyErkki KolehmainenDusan Loossubject
DenticityStructure analysisStereochemistryChemistry010405 organic chemistryX-rayGeneral ChemistryCarbon-13 NMRRing (chemistry)010402 general chemistryMedicinal chemistry01 natural sciences0104 chemical sciencesdescription
The 1H and 13C NMR spectral assignments of ethyl 2-aroyl-4,5-dimethyl-1,2,3,6-tetrahydropyridazine-1-carboxylates (1a-1h) and ethyl 2-arylcarbamoyl-4,5-dimethyl-1,2,3,6-tetrahydropyridazine-1-carboxylates (2a-2k) are given based on DQF COSY, 1H,13C HMQC and 1H,13C HMBC-measurements; the dynamics of the tetrahydropyridazine ring has been studied by 1H, 1H EXSY-technique and the structure of one congener (4′-methylphenyl-derivative, 2a) has been confirmed by X-ray structure analysis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-03-01 | Journal of Chemical Research |