6533b825fe1ef96bd128274f
RESEARCH PRODUCT
ChemInform Abstract: Reaction of 2-Acetyltetralone with Some Esters of Benzoic Acid.
Giacomo FontanaA. ArcoleoM. GottusoGaetano GiammonaG. Abbatesubject
inorganic chemicalschemistry.chemical_compoundChemistryChlorine atomAlkoxy groupNucleophilic substitutionOrder (group theory)General MedicineMedicinal chemistryBenzoic aciddescription
In order to investigate the pharmacological screening of a number of pyran-4-ones their synthesis by cyclization with sulphuric acid of the corresponding 1,3,5-triketones has been carried out with high yields. In the course of preparation of the latter the reaction of 2-acetyltetralone with some esters of benzoic acid derivatives has been studied and in particular, for a number of them, an interesting nucleophilic substitution of a chlorine atom with an alkoxy group on a benzenic nucleus has been evidenced.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-05-12 | ChemInform |