6533b825fe1ef96bd128296c
RESEARCH PRODUCT
Elastic Properties and Line Tension of Self-Assembled Bilayer Membranes
An-chang ShiKyle A. PastorJianfeng LiFriederike SchmidJiajia Zhousubject
Materials scienceLipid BilayersNormal DistributionFOS: Physical sciencesNanotechnology02 engineering and technologyCondensed Matter - Soft Condensed MatterMolecular Dynamics Simulation01 natural sciencesQuantitative Biology::Subcellular Processes0103 physical sciencesMonolayerAmphiphileSoft matterPhysics - Biological Physics010306 general physicsElastic modulusPhysics::Biological PhysicsBilayerLinear elasticityCell MembraneLipid bilayer mechanics021001 nanoscience & nanotechnologyElasticityCondensed Matter::Soft Condensed MatterMembraneNonlinear DynamicsChemical physicsBiological Physics (physics.bio-ph)ThermodynamicsSoft Condensed Matter (cond-mat.soft)0210 nano-technologydescription
The elastic properties of a self-assembled bilayer membrane are studied using the self-consistent field theory, applied to a model system composed of flexible amphiphilic chains dissolved in hydrophilic polymeric solvents. Examining the free energy of bilayer membranes with different geometries allows us to calculate their bending modulus, Gaussian modulus, two fourth-order membrane moduli, and the line tension. The dependence of these parameters on the microscopic characteristics of the amphiphilic chain, characterized by the volume fraction of the hydrophilic component, is systematically studied. The theoretical predictions are compared with the results from a simple monolayer model, which approximates a bilayer membrane by two monolayers. Finally the region of validity of the linear elasticity theory is analyzed by examining the higher-order contributions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-07-01 |