6533b825fe1ef96bd1283115
RESEARCH PRODUCT
Reactions of Carbonyl Compounds in Basic Solutions. Part 351: The Alkaline Hydrolysis and Reactivity – Structure – Spectra Correlations of (Z)-4-(Substituted Benzylidene)-2-Phenyl-4H-Oxazol-5-Ones
Gauguik S. MelikianErkki KolehmainenNelli KiriakossianAlexander PerjéssyKatri LaihiaKeith BowdenMaija NissinenJán BenkoWalter M. F. FabianGa HritzovaVigen O. TaupuzianOlGa Vollarovasubject
ChemistryKineticsOrganic chemistryReactivity (chemistry)General ChemistryElectronic structureNuclear magnetic resonance spectroscopyAlkaline hydrolysis (body disposal)Medicinal chemistrySpectral linedescription
The kinetics of the alkaline hydrolysis and the configuration, conformation and electronic structure were studied using IR, NMR spectroscopy, X-ray analysis and AM1 theoretical calculations for a series of (Z)-4-(substituted benzylidene)-2-phenyl-4H-oxazol-5-ones (1) and compared with analogous results reported for (E)-4-benzylidene-2-phenyl-4H-furan-5-ones (5) and related compounds.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2002-07-01 | Journal of Chemical Research |