FIA-fluorimetric determination of adrenaline in pharmaceutical formulations by oxidation with molecular oxygen

6533b825fe1ef96bd1283194

RESEARCH PRODUCT

FIA-fluorimetric determination of adrenaline in pharmaceutical formulations by oxidation with molecular oxygen

A. Mellado Romero A. Canoves Torres J. Martínez Calatayud

subject

Aqueous solution Chromatography Reducing agent Chemistry Fluorometer Fluorescence spectrometry Molecular oxygen Quantitative analysis (chemistry)Dosage form Fluorescence spectroscopy Analytical Chemistry

description

The fluorimetric determination of adrenaline is carried out in a continuous-flow assembly and by means of the molecular dissolved oxygen. The sample solution merges with an NaOH stream, then the resulting mixture is heated at 73 °C and led to the flow-cell of the fluorimeter. The flow-assembly is very simple and the procedure is quick (107 samples h−1) reproducible (R.S.D. 0.6%), selective and suitable to be applied to determination of adrenaline in formulations. Calibrations graph are linear over the ranges 0.05–15 and 20–40 mgl−1.

year	journal	country	edition	language
1998-09-01	Mikrochimica Acta

https://doi.org/10.1007/bf01243048

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