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RESEARCH PRODUCT

MR Imaging of Perianal Crohn Disease: The Role of Contrast-enhanced Sequences

Roberto LagallaGiuseppe Lo ReDario PiconeSergio SalernoFederico MidiriFederica Vernuccio

subject

medicine.medical_specialtybusiness.industrymedia_common.quotation_subjectMR STIRContrast MediaMagnetic Resonance ImagingMr imaging030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineText miningCrohn DiseasePerianal Crohn diseasemedicineHumansContrast (vision)030211 gastroenterology & hepatologyRadiology Nuclear Medicine and imagingRadiologybusinessmedia_common

description

The MR imaging protocol described by the authors includes contrast-enhanced T1-weighted imaging with fat saturation in all patients except those with poor renal function. Horsthuis et al demonstrated in 2009 the usefulness of contrast-enhanced MR imaging for determining disease activity. Contrast agent administration is also required in case of suspicion of neoplastic tissue complicating fistulas. The joint European Crohn’s and Colitis Organisation–European Society of Gastointestinal and Abdominal Radiology guidelines report that T2-weighted images and contrast-enhanced T1-weighted images are included in the MR imaging protocol for the evaluation of perianal CD. However, as we have demonstrated, an axial T2-weighted fast spinecho sequence with fat saturation, in particular the short inversion time inversion-recovery (STIR) sequence, is a valid alternative to postcontrast T1- weighted fat-saturated imaging, allowing the identification of the primary fistula and any secondary ramification.

10.1148/radiol.2017170721http://hdl.handle.net/10447/245601