6533b826fe1ef96bd128392a

RESEARCH PRODUCT

Triazolopyridines 23.1 Synthesis of 5,5'-bi[1,2,3]triazolo[5,1-a]isoquinoline

Belén Abarca GonzálezRafael Ballesteros CamposBernat Gay RoigJosé-reynaldo Domínguez

subject

Self-coupling and cross-coupling reactionsBitriazoloisoquinolines ; Triazoloisoquinolines ; Lithiation reaction ; Self-coupling and cross-coupling reactionsUNESCO::QUÍMICA:QUÍMICA::Química orgánica [UNESCO]Lithiation reactionUNESCO::QUÍMICA::Química orgánicaBitriazoloisoquinolinesTriazoloisoquinolines:QUÍMICA [UNESCO]

description

5,5'-Bi[1,2,3]triazolo[5,1-a]isoquinoline 6 has been synthesised from [1,2,3]triazolo[5,1-a] isoquinoline 5 by four procedures, dimerisation by LDA, Stille and Suzuki self-coupling reactions, and Suzuki cross-coupling reaction. The last is the best. Compound 6 gives 1,1'- bi(acetoxymethyl)-3,3'-biisoquinoline 10 by triazolo ring opening by acetic acid. Abarca Gonzalez, Belen, Belen.Abarca@uv.es ; Ballesteros Campos, Rafael, Rafael.Ballesteros@uv.es ; Gay Roig, Bernat, bergay@alumni.uv.es

yearjournalcountryeditionlanguage
2004-01-01
http://hdl.handle.net/10550/12898