Synthesis and Tautomerization of 6,7-Dihydro-(1,2,3)-triazolo[1,5-a]pyrimidines.

6533b826fe1ef96bd1284764

RESEARCH PRODUCT

Synthesis and Tautomerization of 6,7-Dihydro-(1,2,3)-triazolo[1,5-a]pyrimidines.

Sergey A. Komykhov Sergey M. Desenko E. S. Gladkov Oleg V. Shishkin Svetlana V. Shishkina V. D. Orlov Herbert Meier

subject

Chemistry Stereochemistry Organic Chemistry Condensation General Medicine Tautomer Medicinal chemistry

description

The condensation of 5-amino-4-phenyl-1,2,3-triazole (1) with chalcones 2a-e or 3-dimethylamino-propiophenone (4f) leads to the 6,7-dihydro-(1,2,3)-triazolo[1,5-a]pyrimidines 3a-f. The equilibrium of 3 and the tautomeric 4,7-dihydro-(1,2,3)-triazolo[1,5-a]pyrimidines 3′ is described.

year	journal	country	edition	language
2007-04-17	ChemInform

https://doi.org/10.1002/chin.200716152

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