6533b826fe1ef96bd1284955

RESEARCH PRODUCT

Efficient and Mild Ytterbium(III)-Catalyzed Tosylation of Alcohols.

S. ComagicRalf Schirrmacher

subject

Ytterbiumchemistry.chemical_classificationOrganic Chemistrychemistry.chemical_elementGeneral MedicineCatalysisAcid anhydrideCatalysisColumn chromatographychemistryYield (chemistry)Organic chemistryLewis acids and basesTrifluoromethanesulfonateAlkyl

description

Ytterbium(III) trifluoromethanesulfonate efficiently catalyzes the reaction of primary and secondary alcohols with toluenesulfonic acid anhydride to yield the alkyl tosylates in high yields. The reactions were carried outunder neutral and mild conditions and product purification was easily achieved by means of short column chromatography.

https://doi.org/10.1002/chin.200437053