Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix

6533b826fe1ef96bd1284e9c

RESEARCH PRODUCT

Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix

Ismael Mingarro Muñoz Paul Whitley Gunnar Von Heijne Mark A. Lemmon

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description

Alanine insertions into the glycophorinA transmembrane helix are found to disrupthelix-helix dimerization in a way thatis fully consistentwith earlier saturation mutagenesis datas,uggesting that Ala-insertion scanning can be used to rapidly map the approximate locatiofn structurally and/or functionally importantsegments in trans-membrane helices

year	journal	country	edition	language
1996-01-01

10.1002/pro.5560050712 https://doi.org/10.1002/pro.5560050712

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