6533b826fe1ef96bd1284f42

RESEARCH PRODUCT

Conformation of the umifenovir cation in the molecular and crystal structures of four carboxylic acid salts

Inese SarcevicaLiana OrolaMikelis V. VeidisArtis KonsAndris Actins

subject

Indole testchemistry.chemical_classificationChloroformAqueous solutionChemistryCarboxylic acidOrganic ChemistryCrystal structureAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundPolymer chemistryMelting pointMoietyOrganic chemistryGentisic acidSpectroscopy

description

The umifenovir salts of maleic, salicylic, glutaric, and gentisic acid as well as the chloroform solvate of the salicylate were prepared. Single crystals of the five compounds were obtained and their molecular and crystal structures determined by X-ray diffraction. In each structure the conformation of phenyl ring with respect to the indole group of the umifenovir moiety is different. The water solubility and melting points of the studied umifenovir salts have been determined.

yearjournalcountryeditionlanguage
2014-01-01Journal of Molecular Structure
https://doi.org/10.1016/j.molstruc.2013.10.010