6533b826fe1ef96bd128507c

RESEARCH PRODUCT

Lack of Association Between Tumor Hypoxia, Glut-1 Expression and Glucose Uptake in Experimental Sarcomas

Oliver ThewsStephan KrausDebra K. KelleherNorbert EsserPeter Vaupel

subject

Pathologymedicine.medical_specialtyChemotherapyTumor hypoxiaTreatment modalitymedicine.medical_treatmentGlucose uptakeCancer researchmedicineBiologyHypoxia (medical)medicine.symptom

description

Hypoxia is a common phenomenon in experimental and human tumors which not only limits the efficacy of non-surgical treatment modalities such as irradiation and 02-dependent chemotherapy but also affects the long-term prognosis of cancer patients. Numerous studies have clearly demonstrated that patients with more hypoxic tumors have a reduced probability for survival and disease-free survival’. For this reason it might be helpful to non-invasively identify patients with hypoxic malignancies.

yearjournalcountryeditionlanguage
2003-01-01
https://doi.org/10.1007/978-1-4615-0205-0_10