New Foldback transposable element TFB1 found in histone genes of the midge Chironomus thummi

6533b827fe1ef96bd1285ada

RESEARCH PRODUCT

New Foldback transposable element TFB1 found in histone genes of the midge Chironomus thummi

Erwin R. Schmidt Th. Hankeln

subject

Genetics Transposable element Base Sequence Foldback (sound engineering)Inverted repeat Molecular Sequence Data Restriction Mapping Gene Amplification Nucleic acid sequence Biology Biological Evolution Chironomidae Histones Transposition (music)Intergenic region Histone Structural Biology Mutation DNA Transposable Elements biology.protein Animals Molecular Biology Gene Repetitive Sequences Nucleic Acid

description

A new Foldback transposable element (TFB1) has been found in the histone H1-H3 intergenic region in the midge Chironomus thummi thummi. TFB1 has long terminal inverted repeats, composed of short, degenerate subrepeats and is flanked by nine or ten base-pair “target site” duplications. TFB1 is present in at least two adjacent histone gene units in Ch. th. thummi, indicating a homogenization of histone gene repeats. The copy number and chromosomal distribution of TFB1 are different in the closely related subspecies Ch. th. thummi and Ch. th. piger, showing that amplification, elimination and transposition of TFB1 have occurred recently during evolution.

year	journal	country	edition	language
1990-10-20	Journal of Molecular Biology

https://doi.org/10.1016/s0022-2836(05)80159-7

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