6533b827fe1ef96bd128651b

RESEARCH PRODUCT

13C NMR of carbonyl compounds. 3. Structure and dynamics of protonated enones and dienones

Klaus MüllenBruno FreiHans SchmicklerEleni Kotzamani

subject

StereochemistryOrganic ChemistryProtonationNuclear magnetic resonance spectroscopyCarbon-13 NMRBiochemistrychemistry.chemical_compound13c nmr spectroscopychemistryComputational chemistryNMR spectroscopy of stereoisomersDrug DiscoverySingle bondEnone

description

Abstract The unsaturated ketones 1 1 – 10 10 were protonated at low temperatures and studied by dynamic 13C NMR spectroscopy. Four interconverting stereoisomers were detected which differ in their conformation with respect to the CO and CC (enone) single bond.

https://doi.org/10.1016/s0040-4039(01)91396-6