6533b827fe1ef96bd128655c
RESEARCH PRODUCT
Larvicidal Activity of Essential Oils of Five Apiaceae Taxa and Some of Their Main Constituents Against Culex quinquefasciatus.
Kevin CianfaglioneKevin CianfaglioneMaurizio BrunoFilippo MaggiGiovanni BenelliGiovanni BenelliRoman Pavelasubject
0106 biological scienceslarvicidal activityInsecticides[SDV]Life Sciences [q-bio]VolatileEnvironmental pollution01 natural sciencesBiochemistrychemistry.chemical_compoundThymolInsecticideTraditional medicinebiologyCulex quinquefasciatusAmmiGeneral Medicineselected main constituentMyristicinCulexLarvaEchinophoraMolecular MedicineDrugcomic_books.characterSabineneBioengineeringessential oilDose-Response RelationshipStructure-Activity RelationshipCulex quinquefasciatuselected main constituentsOils VolatileAnimalsMolecular Biologyessential oilsApiaceaeDose-Response Relationship Drug010405 organic chemistryHeracleum sphondyliumAnimalGeneral Chemistrybiology.organism_classification0104 chemical sciencesFive Apiaceae taxachemistry13. Climate actioncomic_booksOils010606 plant biology & botanyCulex quinquefasciatus; essential oils; Five Apiaceae taxa; larvicidal activity; selected main constituents; Animals; Apiaceae; Culex; Dose-Response Relationship Drug; Insecticides; Larva; Oils Volatile; Structure-Activity RelationshipApiaceaedescription
Apiaceae are aromatic herbs producing essential oils which are used on an industrial scale for various purposes. Notably, Apiaceae essential oils may replace synthetic insecticides keeping most of their efficacy and avoiding environmental pollution and human poisoning. In the present work, we explored the insecticidal potential of the essential oils from five Apiaceae taxa, namely Sison amomum, Echinophora spinosa, Heracleum sphondylium subsp. sphondylium, Heracleum sphondylium subsp. ternatum, and Trachyspemum ammi, as well as their major constituents (sabinene, p-cymene, terpinolene, myristicin, and thymol), against the filariasis vector Culex quinquefasciatus. For the purpose, the essential oils were obtained by hydrodistillation and their composition was achieved by gas chromatography/mass spectrometry (GC/MS). Their acute toxicity on third instar larvae of C. quinquefasciatus was determined. The two most active essential oils were those from T. ammi fruits and E. spinosa roots, showing LC50 below 20 μl/l and LD90 below 50 μl/l. These oils were dominated by the monoterpene phenol thymol and the phenylpropanoid myristicin, respectively, which showed the strongest larvicidal activity (LC50 of 15.1 and 16.3 μl/l, respectively) among the pure compounds tested. These results showed that Apiaceae may be useful as source of larvicidal compounds to be used for the development of cheap, effective and eco-friendly insecticidal formulations.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-01-01 | Chemistrybiodiversity |