6533b827fe1ef96bd1286571
RESEARCH PRODUCT
Ancient human DNA.
Joachim BurgerKarola Kirsanowsubject
Human dnaPopulation DynamicsPaleontologyReproducibility of ResultsHominidaeGeneral MedicineBiological evolutionDNABiologyBiological EvolutionDNA sequencingSpecimen HandlingPaleontologyAncient DNAPhenotypeDna geneticsEvolutionary biologyAnimalsHumansAnatomyPhylogenyDevelopmental Biologydescription
The contribution of palaeogenetic data to the study of various aspects of hominin biology and evolution has been significant, and has the potential to increase substantially with the widespread implementation of next generation sequencing techniques. Here we discuss the present state-of-the-art of ancient human DNA analysis and the characteristics of hominin aDNA that make sequence validation particularly complex. A brief overview of the development of anthropological palaeogenetic analysis is given to illustrate the technical challenges motivating recent technological advancements.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-07-05 | Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft |