6533b827fe1ef96bd1286591

RESEARCH PRODUCT

Visualization of Simulated Arrhythmias due to Gap Junctions

Cesare ValentiMichele MiglioreAntonio Ienna

subject

0301 basic medicine030103 biophysicsComputational modelSettore INF/01 - InformaticaComputer scienceInterface (computing)Gap junctionPremature BeatsCardiac cellVisualization03 medical and health sciencesRepresentation (mathematics)Gap junctions erratic arrhythmias Neuron simulation Blender renderingSimulation

description

New computational models are able to simulate details of cardiac cell networks. Their results allow a better understanding of the functionality of the heart and suggest possible actions to reduce non-fatal premature beats that can give rise to serious diseases. We developed a user-friendly interface to organize Neuron simulations and to present in real-time a three-dimensional representation of the electrical activity due to the gap junctions which interconnect the cells inside cardiac tissues. All physiological parameters were set according to real experimental observations and compared against different types of arrhythmias, retrieved from the Physionet Data Base.

https://doi.org/10.1145/3274005.3274011