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RESEARCH PRODUCT
Extracellular Vesicles from Plants: Current Knowledge and Open Questions.
Riccardo AlessandroRiccardo AlessandroStefania RaimondoOrnella Urzìsubject
QH301-705.5anti-tumor effectsComputational biologyReviewanti-tumor effectBiologyomics characterizationExtracellular vesiclesCatalysisInorganic ChemistryExtracellular VesiclesDrug Delivery Systemsanti-inflammatory effectsdrug-delivery vehicleBiological propertyAnimalsHumansPhysical and Theoretical ChemistryBiology (General)Molecular BiologyQD1-999Spectroscopydrug-delivery vehiclesOrganic ChemistryProteinsGeneral MedicinePlantsLipidsComputer Science Applicationsplant-derived extracellular vesiclesChemistryanti-inflammatory effectRNAdescription
The scientific interest in the beneficial properties of natural substances has been recognized for decades, as well as the growing attention in extracellular vesicles (EVs) released by different organisms, in particular from animal cells. However, there is increasing interest in the isolation and biological and functional characterization of these lipoproteic structures in the plant kingdom. Similar to animal vesicles, these plant-derived extracellular vesicles (PDEVs) exhibit a complex content of small RNAs, proteins, lipids, and other metabolites. This sophisticated composition enables PDEVs to be therapeutically attractive. In this review, we report and discuss current knowledge on PDEVs in terms of isolation, characterization of their content, biological properties, and potential use as drug delivery systems. In conclusion, we outline controversial issues on which the scientific community shall focus the attention shortly.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-05-20 | International journal of molecular sciences |