Zymomonas mobilis atjūgtā enerģētiskā metabolisma pētījumi

6533b827fe1ef96bd1286a23

RESEARCH PRODUCT

Zymomonas mobilis atjūgtā enerģētiskā metabolisma pētījumi

subject

Dzīvās dabas zinātnes Bioloģija

description

Baktērijām Z. mobilis ir raksturīgs augsts no biosintēzes reakcijām neatkarīgs katabolisma ātrums, jeb atjūgtais enerģētiskais metabolisms. Šīs parādības mehanismi kā arī elpošanas ķēdes loma enerģijas apritē līdz galam nav skaidra. Disertācijas „Zymomonas mobilis atjūgtā enerģētiskā metabolisma pētījumi“ mērķi bija (I) izpētīt Z. mobilis elpošanas ķēdes strukturālās un funkcionālās īpatnības un tās saistību ar atjūgto metabolismu, (II) konstruēt in silico centrāla katabolisma modeli un ar tā palīdzību pētīt katabolisma regulāciju. Darbā secināts: (I) oksidatīvās fosforilēšanas trūkums Z. mobilis ir skaidrojams ar nepietiekamu protondzinējspēka un H+-atkarīgās ATFāzes enerģētisku sajūgšanu, (II) Z. mobilis katabolisma ātrums netiek kontrolēts tieši Entnera-Dudorova ceļā, bet primāri ir atkarīgs no ATF patērējošo reakciju aktivitātes. Atslēgas vārdi: Zymomonas mobilis, atjūgtā augšana, elpošanas ķēde, in silico modelis, H+-atkarīgā ATFāze.

year	journal	country	edition	language
2014-01-01

https://dspace.lu.lv/dspace/handle/7/3738

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