6533b827fe1ef96bd128723b
RESEARCH PRODUCT
Surface roughness, porosity, and texture as modifiers of cellular adhesion.
Theo G. Van KootenClare E. ShannonJörg MeyleCarolyn E. CannonAndreas F. Von RecumKenwyn J. Longsubject
MicrometreMaterials scienceBiocompatibilityLaser scanningConfocal microscopylawScanning electron microscopeGeneral EngineeringSurface roughnessTexture (crystalline)Composite materialPorositylaw.inventiondescription
Substrate topography in the micrometer range is reviewed as a modifier of the response of cultured cells and of biocompatibility when implanted into tissues. Characterization methods for substrate topography are discussed, including scanning electron microscopy, profilometry, laser scanning, and confocal microscopy. Because of the current technical limitations in reproducing micron-level topographic details, only one method, ion-beam etching, has been found suitable for texturing substrates on nonplanar surfaces.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-11-03 | Tissue engineering |