6533b828fe1ef96bd12878d1

RESEARCH PRODUCT

Sequenom MassARRAY Technology for the Analysis of DNA Methylation

Marisa IborraEnrique Busó

subject

Clinical PracticeNovel techniqueMethylation analysisDNA methylationEpigeneticsBiologyBioinformatics

description

Abstract DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression and is involved in the development of different pathologies such as obesity, Alzheimer's, and cancer. In this chapter, we have analyzed in depth the Sequenom MassARRAY® technology for the analysis of DNA methylation with special emphasis on its applications in clinical practice. In recent years, the Sequenom EpiTYPER® system technology has emerged as a novel technique for methylation analysis that offers a high range of options with great performance and several advantages.

https://doi.org/10.1016/b978-0-12-801899-6.00007-3