6533b828fe1ef96bd1287adc
RESEARCH PRODUCT
Pyrido[4′,3′:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazines, a new class of Temozolomide heteroanalogues
Patrizia DianaAntonina StagnoPaola BarrajaAnna CarboneAlessandra MontalbanoAnnamaria MartoranaGaetano DattoloGirolamo Cirrincionesubject
Temozolomide heteroanaloguesOrganic ChemistrySettore CHIM/08 - Chimica Farmaceuticadescription
A series of derivatives of new ring system pyrido[4’,3’:4,5]pyrrolo[2,1-d] [1,2,3,5]tetrazine was obtained from moderate to excellent yields by reaction of 2-diazo-3-ethoxycarbonyl-pyrrolo[2,3- c]pyridine with alkyl- or aryl-isocyanates in dichlorometane at room temperature or at 50 °C under microwave irradiation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-05-10 | Arkivoc |