The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)

6533b828fe1ef96bd1287b27

RESEARCH PRODUCT

The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)

Caldas M.Perez-aisa A.Tepes B.Keco-huerga A.Bujanda L.Lucendo A. J.Rodrigo L.Vaira D.Fernandez-salazar L.Huguet J. M.Perez-lasala J.Jurecic N. B.Fadeenko G.Barrio J.Areia M.Ortuno J.Pellicano R.Leja M.Molina-infante J.Bogomolov P.Alekseenko S.Dominguez-cajal M.Gomez-camarero J.Ntouli V.Martinez-dominguez S. J.Ruiz-zorrilla R.Nunez O.Silkanovna Sarsenbaeva A.Almela P.Phull P.Espada M.Puig I.Nyssen O. P.Megraud F.O'morain C.Gisbert J. P.The Hp-eureg Investigators Gravina Ag Romano M.

subject

Microbiology (medical)medicine.medical_specialty Multivariate analysis Helicobacter pylori statins treatment RM1-950 Biochemistry Microbiology Article statins Rescue therapy Internal medicine In real life Medicine Pharmacology (medical)General Pharmacology Toxicology and Pharmaceutics statins ; Helicobacter pylori ; treatment biology Helicobacter pylori treatment business.industry <i>Helicobacter pylori</i>Statin Statin treatment Helicobacter pylori biology.organism_classification Treatment Infectious Diseases Therapeutics. Pharmacology business

description

Statins could increase the effectiveness of Helicobacter pylori eradication therapies due to their anti-inflammatory effect. The aim of this study was to analyze the impact of this therapeutic association in real life. This is a multicenter, prospective, non-interventional study aimed at evaluating the management of H. pylori by European gastroenterologists. Patients were registered in an e-CRF by AEG-REDCap from 2013 to 2020. The association between statin use and H. pylori eradication effectiveness was evaluated through multivariate analysis. Overall, 9988 and 705 patients received empirical and culture-guided treatment, respectively. Overall, statin use was associated with higher effectiveness in the empirical group (OR = 1.3

year	journal	country	edition	language
2021-08-11

https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=14972

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