ChemInform Abstract: A New Tandem Cross Metathesis-Intramolecular Aza-Michael Reaction for the Synthesis of α,α-Difluorinated Lactams.

6533b828fe1ef96bd128821e

RESEARCH PRODUCT

ChemInform Abstract: A New Tandem Cross Metathesis-Intramolecular Aza-Michael Reaction for the Synthesis of α,α-Difluorinated Lactams.

Carlos Del Pozo Santos Fustero Amparo Asensio Javier Miró María Sánchez-roselló Claribel Báez

subject

chemistry.chemical_compound Tandem Chemistry Intramolecular force Methyl vinyl ketone Michael reaction Salt metathesis reaction Organic chemistry General Medicine Optically active Metathesis Pyrrole derivatives

description

Difluorinated amides are treated with methyl vinyl ketone or analogous esters to produce the desired γ- and δ-lactam units including optically active versions.

year	journal	country	edition	language
2012-09-07	ChemInform

https://doi.org/10.1002/chin.201240131

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