Epizodiskas vispārējas un audu hipoksijas izraisītas vazomotorās adaptīvās reakcijas ādā

6533b828fe1ef96bd128884e

RESEARCH PRODUCT

Epizodiskas vispārējas un audu hipoksijas izraisītas vazomotorās adaptīvās reakcijas ādā

Artūrs Paparde

subject

Dzīvās dabas zinātnes Bioloģija Biology

description

Asins plūsmai mikrocirkulācijas līmenī hipoksijas apstākļos ir svarīga loma, tomēr hipoksijas efekts ir atkarīgs no hipoksijas veida, dziļuma un ilguma. Darba mērķis bija novērtēt akūtas sistēmiskas nepārtrauktas un epizodiskas normobāriskas hipoksijas ietekmi uz ādas mikrocirkulācijas gultni un vietējām adaptācijas reakcijām. Pētījumā piedalījās 65 jauni, veseli, abu dzimumu respondenti. Akūtas hipoksijas ietekmē palielinājās sistēmiskie un reģionālie hemodinamikas parametri, savukārt samazinājās endotēlija atkarīgā vazodilatācija un seruma citokīnu koncentrācijas. Akūta sistēmiska nepārtraukta un epizodiska normobāriska hipoksija izraisa atšķirīgas ādas mikrocirkulācijas gultnes vazomotorās reakcijas, kuras realizējas ar sistēmiskās hemodinamikas iz maiņām un dažādu lokālo regulācijas mehānismu ietekmi uz lokālo hemodinamiku.

year	journal	country	edition	language
2017-01-01

https://dspace.lu.lv/dspace/handle/7/34872

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