6533b828fe1ef96bd1288d58
RESEARCH PRODUCT
The preparation of (14C) and [3H] labelled benzene oxide
Franz OeschKarl L. Plattsubject
Tritiated waterOrganic ChemistryInorganic chemistryOxideHalogenationBiochemistryDecompositionAnalytical Chemistrychemistry.chemical_compoundchemistryDrug DiscoveryOrganic chemistryRadiology Nuclear Medicine and imagingCarbon-14Specific activityTritiumBenzeneSpectroscopydescription
Benzene oxide -[U-14C] was prepared from benzene -(U-14C) by modifications of methods described for the inactive compound. Benzene oxide-[3.6–3H] was prepared by decomposition of 3.6-bis-trimethylsilyl-1,4-cyclohexadiene with tritiated water. bromination of the 1,4-cyclohexadiene-[3,6-3H] so obtained. epoxidation and dehydrobromination. With the latter method benzene oxide-[3,6–3H] can be prepared at a much lower cost and higher specific activity than benzene oxide-[U-14C].
year | journal | country | edition | language |
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1977-01-01 | Journal of Labelled Compounds and Radiopharmaceuticals |