6533b829fe1ef96bd128970c

RESEARCH PRODUCT

Recent advances in on-line liquid chromatography - infrared spectrometry (LC-IR)

J. KuligowskiG. QuintásS. GarriguesB. LendlM. De La GuardiaB. Lendl

subject

ChemometricsChromatographyBackground CorrectionResolution (mass spectrometry)ChemistryInfrared spectroscopyMass spectrometrySpectroscopyAnalytical Chemistry

description

We review advances in isocratic and gradient liquid chromatography hyphenated on-line with infrared spectrometry (LC-IR). We place special emphasis on chemometric background correction and other applications of chemometric algorithms used to improve the sensitivity and the resolution of LC-IR signals. We also comment on recent technical advances, (e.g., dedicated flow-cells and new light sources) and review applications in the technological, cosmetics, environmental and food sectors.

https://doi.org/10.1016/j.trac.2010.03.004