ChemInform Abstract: Base-Catalyzed Isomerization of 2-Isoxazolines Enables a Two-Step Enantioselective Synthesis of β-Hydroxynitriles from Enals.

6533b829fe1ef96bd128a1f6

RESEARCH PRODUCT

ChemInform Abstract: Base-Catalyzed Isomerization of 2-Isoxazolines Enables a Two-Step Enantioselective Synthesis of β-Hydroxynitriles from Enals.

Petri M. Pihko Antti Pohjakallio Jun Liu

subject

inorganic chemicals genetic structures Chemistry organic chemicals Two step Enantioselective synthesis General Medicine Optically active Base (exponentiation)Isomerization Combinatorial chemistry eye diseases Catalysis

description

Treatment of chiral isoxazoles with catalytic amounts of DBU results in efficient formation of optically active β-hydroxynitriles.

year	journal	country	edition	language
2011-01-20	ChemInform

https://doi.org/10.1002/chin.201107076

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