6533b829fe1ef96bd128a575
RESEARCH PRODUCT
From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia
Mikko NikinmaaJoachim FandreyT. HankelnHideo YamagataNora B. TerwilligerDavid HoogewijsKatja HeiseJ. A. Powell-coffmanShin-ichi TokishitaSven PåhlmanK. A. WebsterThomas A. GorrP. H. MaxwellKalle T. RytkönenDoris AbeleMagnus LucassenThorsten Burmestersubject
0303 health sciencesbusiness.industryHypoxia (environmental)610 Medicine & healthPlant Science10081 Institute of Veterinary Physiology3. Good health03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisInternational congress10076 Center for Integrative Human Physiology1110 Plant ScienceMedicine570 Life sciences; biologyAnimal Science and Zoology1103 Animal Science and ZoologybusinessOxygen sensingNeuroscience030304 developmental biologydescription
The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O(2) sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-06-16 |