6533b829fe1ef96bd128aea1
RESEARCH PRODUCT
High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor
Ngong Kodiah BeyehNgong Kodiah BeyehIsabel DíezJohn F. TrantAndrew L. FeigS. Maryamdokht TaimooryDaniel MeisterRobin H. A. RasKari Rissanensubject
pyrophosphatereceptors010402 general chemistryMass spectrometry01 natural sciencesPyrophosphateChloridemolecular diagnosticschemistry.chemical_compoundmedicineresorcinarenesta116Biochemistry Biophysics and Structural Biologyta114010405 organic chemistryIsothermal titration calorimetryGeneral ChemistryResorcinarenePhosphateCombinatorial chemistryOrders of magnitude (mass)0104 chemical sciencesChemistrychemistrySelectivitymedicine.drugdescription
N-Alkyl ammonium resorcinarenes selectively bind pyrophosphate in pure water with an exceptionally high binding constant of up to 1.60 × 107 M–1, three orders of magnitude higher than ATP.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-12-07 |