6533b829fe1ef96bd128af88

RESEARCH PRODUCT

Homing and memory patterns of human gammadelta T cells in physiopathological situations.

Luca BattistiniDaniela F. AngeliniMaria Teresa CencioniFrancesco DieliNadia CaccamoSerena MeravigliaGiovanna BorsellinoAlfredo Salerno

subject

EffectorImmunologyT lymphocyteBiologymedicine.disease_causeInfectionsLymphocyte ActivationMicrobiologyAutoimmunityAutoimmune DiseasesHeterogeneous populationInfectious DiseasesT-Lymphocyte SubsetsSurface markerImmunologymedicineHumansTuberculosisEffector functionsMalaria FalciparumProtozoal diseaseImmunologic MemoryHoming (hematopoietic)

description

Vgamma9Vdelta2 are a heterogeneous population of T cells and comprise distinct naive, memory and effector populations that can be distinguished on the basis of surface marker expression and effector functions. We review here these recently studied features of Vgamma9Vdelta2 T lymphocyte biology and the roles they play in infectious and autoimmune diseases.

10.1016/j.micinf.2004.12.008https://pubmed.ncbi.nlm.nih.gov/15804491